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中药化学

郭力

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个人简介

郭力,博士,教授,博士生导师,药学院;国务院政府津贴获得者,四川省学术和技术带头人,四川省中医药学术和技术带头人,四川省有突出贡献优秀专家,国家自然基金生命科学部函审专家,四川省食药监局药品审评专家;长期从事中药化学成分与质量标准化研究,探索和阐明中药药效物质基础,重点围绕川产道地药材附子、石斛、川芎等品种的化学成分、炮制、配伍等多方面展开研究,对建立其质量控制体系进行了积极探索。近五年来主持主研科研项目10余项,主持参与国家自然科学基金项目2项,国家科技部项目1项四川省创新团队项目2项四川省科技厅项目2项;发表论文80余篇(SCI收录20余篇),出版专著20余部;申请专利30项(授权14项);获国家科技进步二等奖1次,获省科技进步一等奖3次;培养博士、硕士研究生50余人。

 

代表性成果

(1)成都中医药大学,中药学学科特色创新科研团队,CXTD2018012,川产道地药材综合研究与应用开发创新团队,2018-06至2020-06,100万元,在研,主持

(2)国家科技部,国家重点研发项目,2017YFC1701804,高品质道地药材中药材附子规模化种植及精准扶贫示范研究,2018-01至2021-12,425万元,在研,主研

(3)四川省科技厅,四川省科技基础条件平台项目,2019JDPT0032,四川省中药化合物资源共享平台,2019-01至2021-12,30万元,在研主研

(4)国家自然科学基金,区域创新发展联合基金,U19A2010,川产道地药材的道地性研究,2020-01至2023-12,247万元,在研,主研

(5) Xiao Haijun#; Guo Yiping#; Liu Hongmei; Liu Yushi; Wang Yumin; Li Changqing; Jaroslav Císař; David Škoda; Ivo Kuřitka; Guo Li*; Vladimír Sedlaříkp*; Structure-based design of charge-conversional drug self-delivery systems for better targeted cancer therapy, Biomaterials, 2020, 232.

(6) Li He#; Qian Su#; Lan Bai#; Meifeng Li; Juanru Liu; Xiaomei Liu; Cunyan Zhang; Zhongliang Jiang; Jun He; Jianyou Shi*; Shan Huang*; Li Guo*; Recent research progress on natural small molecule bibenzyls and its derivatives in Dendrobium species, European Journal of Medicinal Chemistry, 2020, 112530.

(7) Zhang Zhen##; Jiang Maoyuan#; Wei Xinyi; Shi Jingfeng; Geng Zhao; Yang Shasah; Fu Chaomei*; Guo Li*; Rapid discovery of chemical constituents and absorbed components in rat serum after oral administration of Fuzi-Lizhong pill based on high-throughput HPLC-Q-TOF/MS analysis, Chinese Medcine, 2019, 14(6): 1-22.

(8) Liu Hongmei; Fang Chengxin; Zhang Tingmo; Guo Li*; Ye Qiang*; Molecular authentication and differentiation of Dendrobium species by rDNA ITS region sequence analysis, AMB Express, 2019, 9(53): 1-9

(9) Ye Qiang; Liu Hongmei; Fang Chengxin; Liu Yushi; Liu Xiaomei; Liu Juanru; Zhang Cunyan; Zhang Tingmo; Peng Cheng*; Guo Li*; Cardiotoxicity evaluation and comparison of diterpene alkaloids on zebrafish, Drug and Chemical Toxicology, 2019: 1-8.

(10) Zhang Xiao; Zou, Lihua; He Yulin; Peng Cheng; Guo Li*; Xiong Liang*. Triterpenoid saponins from the buds of Lonicera similis. Natural Product Research, 2018, 32: 2282-2290.

 

终审:药学院管理员
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